The nurse is performing an assessment on a patient receiving ticarcillin (Ticar) for treatment of a Pseudomonas infection. Which of the following clinical manifestations should most concern the nurse? (Select all that apply.)
a. High sodium level and edema
b. Transient headache
c. Gastrointestinal (GI) discomfort
d. Poor skin turgor
e. Bleeding gums
A
E
Because the drug is administered as disodium salt, and large intravenous (IV) doses often are required, symptoms of sodium overload (CHF) may develop. Edema would be an indication of potential fluid overload, especially coupled with a high sodium level. Also, ticarcillin interferes with platelet function and can promote bleeding. Bleeding gums are a good indication that plate-let function may be compromised.
A transient headache, GI discomfort, and poor skin turgor may signal other problems, but they are not consistent with administration of ticarcillin.
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