Oncogenic mutations in Ras, Src and ErbB2 genes commonly seen in tumors typically involve __________
a) Increased tyrosine phosphorylation of these 3 proto-oncogenes
b) Disruption of the protein's on/off control
c) Nonsense mutations that result in little or no protein being expressed
d) Changes in protein shape that result in completely different protein binding partners
Answer: b) Disruption of the protein's on/off control
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