The nurse, administering an infusion of vancomycin, will observe the client for which symptoms of red man syndrome?
Standard Text: Select all that apply.
1. Reddening of the upper body
2. Hypotension
3. Reflex tachycardia
4. Headache
5. Seizure
Correct Answer: 1,2,3
Rationale 1: This is the classic symptom of red man syndrome.
Rationale 2: The release of histamine results in vasodilation, leading to hypotension.
Rationale 3: The release of histamine results in vasodilation, leading to reflex tachycardia.
Rationale 4: Headache may be a sign of neurotoxicity.
Rationale 5: Seizure activity may indicate neurotoxicity.
Global Rationale: Vancomycin may cause a syndrome of flushing, hypotension, tachycardia, and rash on the upper body, a condition called the red man syndrome.
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