The first abnormality described in the lymphomas was in Burkitt lymphoma. This first demonstration of a proto-oncogene that was translocated to a location known to be active in B-cell lymphoma,
resulting in the activation of the oncogene, was at what heavy chain locus?
a. t(12;21)
b. t(8;14)
c. 14q32
d. P13;q22
Correct Answer: C
Health Professions
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