The client has a medical diagnosis of multiple sclerosis and receives modafinil (Provigil). Which evaluation by the nurse would most likely indicate a therapeutic response to this drug?
1. Improved appetite and ability to eat
2. Reduction of pain and anxiety
3. Decreased myelin swelling and inflammation
4. Increased alertness and energy
Correct Answer: 4
Rationale 1: This drug actually might cause anorexia rather than improve appetite.
Rationale 2: Provigil does not affect pain or anxiety (GABA) receptors, and it is not an anti-inflammatory agent.
Rationale 3: Provigil does not affect pain or anxiety (GABA) receptors, and it is not an anti-inflammatory agent.
Rationale 4: Modafinil is an alpha-1 adrenergic agent that is thought to activate receptors that respond to the neurotransmitter norepinephrine in the brain. This results in increased alertness and energy.
Global Rationale: Modafinil is an alpha-1 adrenergic agent that is thought to activate receptors that respond to the neurotransmitter norepinephrine in the brain. This results in increased alertness and energy. This drug actually might cause anorexia rather than improve appetite. Provigil does not affect pain or anxiety (GABA) receptors, and it is not an anti-inflammatory agent. Provigil does not affect pain or anxiety (GABA) receptors, and it is not an anti-inflammatory agent.
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