Tricyclic antidepressants, such as imipramine hydrochloride, have been prescribed for treatment of ADHD (attention deficit hyperactivity disorder) to enhance neural circuit activity because they affect the reuptake of excitatory neurotransmitters
Predict the effect of such drugs on the postsynaptic neuron and explain your rationale.
What will be an ideal response?
Answer: Tricyclic antidepressants inhibit neurotransmitter reuptake, allowing excitatory neurotransmitter to remain in the synaptic cleft for longer periods of time, during which they increase the number of successive action potentials generated by the postsynaptic neuron.
You might also like to view...
Structurally and functionally related groups of proteins are referred to as:
A. domains B. relatives C. realms D. families E. spheres
ATP is a good energy currency for cells because it has a(n) _____________ amount of Gibbs free energy
A. very low B. intermediate C. very high
Skeletal muscle can operate anaerobically for short periods, producing ________ and a small amount of ATP
a. lactate b. pyruvate c. creatine d. phosphate
Nervous tissue provides movement and heat
a. true b. false