A patient is admitted for treatment of gout that has been refractory to treatment with allopurinol and probenecid. The patient is taking colchicine, and the prescriber orders pegloticase (Krystexxa)
Before administering this drug, the nurse will expect to:
a. administer an antihistamine and a glucocorticoid.
b. discontinue the colchicine.
c. increase the dose of colchicine.
d. prepare to administer a bronchodilator if needed.
ANS: A
Because pegloticase poses a risk of triggering anaphylaxis, patients should be pretreated with an antihistamine and a glucocorticoid. Colchicine is indicated at the initiation of treatment with pegloticase to reduce the intensity of gout flare-ups. Bronchodilators are not indicated.
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What critical piece of information is missing from the following medication order: Amoxicillin 250 mg every 8 hours?
A) Dose B) Route C) Frequency D) Trade name of the drug
A patient sustained multiple fractures and contusions when hit by a car while walking across the street. He says, "How can I be hurt so badly? The car barely hit me.". How should the nurse respond?
1. "Your body absorbed a lot of energy from the moving car.". 2. "Because you are diabetic, your injuries are worse.". 3. "You probably don't remember how hard you were hit.". 4. "Because you are older, your injuries are worse.".
If a physician suspects a qualitative platelet defect, the most useful test to order is the
A. Platelet count B. Prothrombin time C. 5.OM urea solubility test D. Bleeding time