College students were given various amounts of alcohol within a specified timeframe and then asked to drive an obstacle course
The rationale for poor performance in driving as the amount of alcohol intake increased includes, "The blood–brain barrier:
A) Allows more bilirubin to cross the barrier producing brain damage."
B) Allows alcohol, a very lipid-soluble molecule to rapidly enter the brain."
C) Excludes water-based compounds from crossing the brain with the exception of alcohol."
D) Interacts negatively with the potassium–sodium pump, allowing alcohol to freely flow into the capillaries of the brain."
Ans: B
Feedback:
The blood–brain barrier prevents many drugs from entering the brain. Most highly water-soluble compounds are excluded from the brain, especially molecules with high ionic charge, such as many of the catecholamines. In contrast, many lipid-soluble molecules cross the lipid layers of the blood–brain barrier with ease. Alcohol, nicotine, and heroin are very lipid soluble and rapidly enter the brain.
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