Which biochemical pathway fits the data presented?

Assume that a series of compounds has been discovered in Neurospora. Compounds A–F appear to be intermediates in a biochemical pathway. Conversion of one intermediate to the next is controlled by enzymes that are encoded by genes. Several mutations in these genes have been identified and Neurospora strains 1–4 each contain a single mutation. Strains 1-4 are grown on minimal media supplemented with one of the compounds A-F. The ability of each strain to grow when supplemented with different compounds is shown in the table (+ = growth; o = no growth).



media supplement



A) A ? B ? C ? D ? E ? F

B) A ? B ? C ? F ? D ? E

C) F ? B ? C ? D ? A ? E

D) A ? B ? C ? D ? F ? E

E) A ? B ? F ? E ? C ? D


D) A ? B ? C ? D ? F ? E

Biology & Microbiology

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