A client prescribed olanzapine (Zyprexa) for mania associated with bipolar disorder is being discharged. Which client statement indicates more teaching is necessary about this medication?

1. "I take St. John's wort at bedtime to help me go to sleep."
2. "I'm going to weigh myself weekly to check for weight gain."
3. "I need to report symptoms of extreme thirst, insatiable hunger with weight loss, and increased urination."
4. "I might need to increase my intake of fiber and fluids."


Correct Answer: 1
Rationale 1: Increased central nervous system depression can occur if atypical antipsychotics are taken with St. John's wort or valerian.
Rationale 2: Weight gain is a frequent adverse effect of atypical antipsychotics.
Rationale 3: The risk of developing type 2 diabetes is greater with this medication, so it is important to assess for symptoms.
Rationale 4: Constipation is a frequent adverse effect of atypical antipsychotics.
Global Rationale: Increased central nervous system depression can occur if atypical antipsychotics are taken with St. John's wort or valerian. Weight gain and constipation are frequent adverse effects of atypical antipsychotics. The risk of developing type 2 diabetes is greater with this medication, so it is important to assess for symptoms.

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