In meiosis, sister kinetochores are attached to the same pole of the cell during meiosis I, and sister chromatid cohesion is released during anaphase II. What would be the likely result if sister kinetochores were attached to different poles of the cell during meiosis I and sister chromatid cohesion was released during anaphase I?

Question

A.  Sister chromatids would migrate to opposite poles during anaphase I.
B.  Sister chromatids would migrate to opposite poles during anaphase II.
C.  Sister chromatids would migrate to the same pole during anaphase I.
D.  Sister chromatids would migrate to the same pole during anaphase II.

Clarify Question
· What is the key concept addressed by the question?
· What type of thinking is required?
· What key words does the question contain and what do they mean?

  Gather Content
  · What do you know about separation of sister chromatids? How does it relate to the question?

  Consider Possibilities  
  · What other information is related to the question? Which information is most useful?

  Choose Answer
  · Given what you now know, what information and/or problem solving approach is most likely to produce the correct answer?  

  Reflect on Process
  · Did your problem-solving process lead you to the correct answer? If not, where did the process break down or lead you astray? How can you revise your approach to produce a more desirable result?

Answer 1

A.  Sister chromatids would migrate to opposite poles during anaphase I.

Clarify Question
  · What is the key concept addressed by the question?
        o The question asks about separation of sister chromatids in meiosis.
· What type of thinking is required?
        o You are being asked to apply your knowledge of sister chromatids to predict what would happen if the separated in anaphase I of meiosis.
· What key words does the question contain and what do they mean?
        o Sister chromatid cohesin was released during anaphase I – this means that the sister chromatids would separate during meiosis.

  Gather Content
  · What do you know about separation of sister chromatids? How does it relate to the question?
        o Normally sister chromatids remain attached during meiosis I and anaphase I.  The sister chromatids then separate during anaphase II of meiosis II.
  Consider Possibilities  
  · What other information is related to the question? Which information is most useful?
        o If the kinetochore microtubules attach to opposite poles then the sister chromatids would move to opposite poles of the cell.
        o If the chromatid cohesin that holds sister chromatids together was released during anaphase I then the sister chromatids would separate in anaphase I.

  Choose Answer
  · Given what you now know, what information and/or problem solving approach is most likely to produce the correct answer?  
        o The cohesin being released in anaphase I and kinetochore microtubules attached to opposite poles of the cell would result in the sister chromatids migrating to opposite poles in anaphase I.

  Reflect on Process
  · Did your problem-solving process lead you to the correct answer? If not, where did the process break down or lead you astray? How can you revise your approach to produce a more desirable result?
        o This question asked you to apply your understanding of the separation of sister chromatids to predict what would happen if this occurred in anaphase I. If you got the correct answer, great job! If you got an incorrect answer, where did the process break down? Did you recall that once cohesin is released the sister chromatids separate?  Did you realize that if the kinetochore microtubules attach to different poles of the cell, the sister chromatids will migrate to opposite poles.