How can microarrays differentiate between a wild-type allele and a disease allele that differ at only one nucleotide?

A) The DNA sequences of both alleles are determined.
B) Oligonucleotides hybridize with the two alleles differently.
C) Polymerase chain reaction primers amplify DNA from one allele, but not the other.
D) Microarrays are not capable of detecting a difference between those alleles.


B) Oligonucleotides hybridize with the two alleles differently.

Biology & Microbiology

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A three-hectare lake in the American Midwest suddenly has succumbed to an algal bloom. What is the likely cause of eutrophication in freshwater ecosystems, such as this one?

A) increased solar radiation B) introduction of non-native tertiary consumer fish C) nutrient runoff D) accidental introduction of a prolific culture of algae E) iron dust blowing into the lake

Biology & Microbiology

The lipid group that is the major component of cell membranes is the ________.

A. triglycerides B. steroids C. waxes D. prostaglandins E. phospholipids

Biology & Microbiology

Which of the following is not a secondary

sexual trait? a. rounded hips in females. b. deep voice in males. c. facial hair in males. d. rounded breasts in female. e. testes in males

Biology & Microbiology

In mammals, individuals with two X chromosomes are female, and individuals with an X and a Y chromosome are male

It had long been known that a gene located on the Y chromosome was sufficient to induce the gonads to form testes, which is the main male-determining factor in development, and researchers sought the product of this gene, the so-called testes-determining factor (TDF). For several years, the TDF was incorrectly thought to be a zinc finger protein encoded by a gene called BoY. Which of the following observations would most strongly suggest that BoY might not be the TDF? Explain your answer. (a) Some XY individuals that develop into females have mutations in a different gene, SRY, but are normal at BoY. (b) BoY is not expressed in the adult male testes. (c) Expression of BoY in adult females does not masculinize them. (d) A few of the genes that are known to be expressed only in the testes have binding sites for the BoY protein in their upstream regulatory sequences, but most do not.

Biology & Microbiology