The nurse is teaching a class for newly hired cardiac care nurses and is discussing dronedarone (Multaq). What statement, if made by the nurse, is accurate? (Select all that apply.)
A) "Dronedarone has properties of all four classes of antiarrhythmics."
B) "Dronedarone reduces the risk of hospitalization in patients in atrial fibrillation."
C) "Dronedarone has many drug–drug interactions that need to be reviewed."
D) "It is an oral drug taken once a day."
E) "Common adverse effects of dronedarone include ventricular arrhythmias."
A, B, C
Feedback:
Dronedarone has properties of all four classes of antiarrhythmics and the mechanism by which it helps suppress atrial arrhythmias is not fully understood. It is used to reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation or flutter who have risk factors for cardiovascular disease and who are in sinus rhythm or are scheduled to be converted to sinus rhythm. The drug is taken orally twice a day. Many drug–drug interactions have been associated with the drug and this situation should always be reviewed before starting or stopping any drugs while on this drug. Grapefruit juice should not be consumed while taking this drug. The most common adverse effects seen with dronedarone are heart failure, prolonged QT interval, nausea, diarrhea, and rash. It should never be used during pregnancy because it has been associated with fetal abnormalities.
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