An egg of the organism of S. mansoni is isolated from the feces of an adult man who has been traveling in Africa. An unoperculated egg with a large lateral spine is recovered. The patient is administered the standard dose of praziquantel; however, his infection does not improve. Which one of the following statements explains this discrepancy?
a. Metrifonate should have been adminis-tered.
b. Bilarcil is the drug of choice for this type of infection.
c. Steroids should have been initially admi-nistered.
d. A larger dose may be required to be effec-tive against this organism.
D
Based on the morphologic characteristics and patient history, the organism is S. mansoni. The drug of choice for treatment of schistosomiasis infections is praziquantel, administered in two or three doses in a single day. Infection with S. mansoni may require a larger dose than for the other species. An alternative treatment for S. haematobium infections is metrifonate (Bilarcil), an or-ganophosphorus compound, administered once every other week in a total of three doses.
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Answer the following statement true (T) or false (F)