A patient comes to the clinic for a follow-up appointment after being released from the hospital for angina. The nurse is discussing his medication, nitroglycerin
The nurse is correct to state that the principal way this medication relieves the pain of stable angina is by a. strengthening blood pressure.
b. reducing cardiac oxygen demand.
c. promoting vagal stimulation.
d. increasing sympathetic stimulation to the heart.
B
Nitroglycerin reduces the pain of exertional angina primarily by reducing cardiac oxygen demand. Nitroglycerin vasodilates the blood vessels, which facilitates blood pressure but does not strengthen it. Nitrates have a vasodilating effect (ie, they act directly on vascular smooth muscle [VSM] to promote vasodilation) and can cause hypotension.
Nitroglycerin does not promote vagal stimulation or increase sympathetic stimulation to the heart.
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