The anticancer drug paclitaxel (Taxol), derived from the Pacific Yew, has many effects on mitosis. One of its most powerful effects is that it prevents disassembly of the mitotic spindle, which prevents spindle fibers from shortening Which phase of mitosis would this directly affect? Why would this stop cell division overall and lead to cell death?
Answer: The anticancer drug taxol is used in the carcinoma of head, neck, bladder etc. It is an important drug for treating cancer. This drug affect the M phase at either metaphase or anaphase.
This drug prevents the disassembly of spindles fibres at the checkpoint between metaphaase and anaphase of mitosis during cell cycle. Hence, the cell can not move from metaphase to anaphase. which is required for the cell growth and development. This lead to the cell growth inhibition through mitosis and hence lead to the death of the cell by apoptosis.
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A. The majority of the phenotypic variation has a genetic basis B. The majority of the phenotypic variation has an environmental basis C. The trait is polygenic D. There is a significant difference between the two strains
Which includes all of the components that make up the Organ of Corti?
A. the basilar membrane only B. the tectorial and basilar membranes C. hair cells and associated neurons only D. hair cells and the tectorial membrane E. hair cells and the basilar and tectorial membranes
An animal has a diploid chromosome number of 12. An egg cell of that animal has 5 chromosomes. The most probable explanation is
a. normal mitosis. b. normal meiosis. c. nondisjunction in meiosis I. d. nondisjunction in meiosis I or II. e. nondisjunction in mitosis.
Which of the following must occur for a plant or animal to grow and develop normally?
A) The organism must receive a supply of the appropriate hormones from its parents. B) The organism must be able to control the timing and rate of cell division in different parts of its body. C) Sufficient light must be available to stimulate cell division. D) Sufficient oxygen must be available to stimulate cell division.