A client is taking St. John's wort and an SSRI. The nurse observes the client for which symptoms?(Select all that apply.)
1. Mania
2. Confusion
3. Renal failure
4. Tachycardia
5. Hypotension
1, 2, 3
Rationale 1: Mania is a sign of serotonin syndrome, which can occur when St. John's wort is taken with an SSRI.
Rationale 2: Confusion is a sign of serotonin syndrome, which can occur when St. John's wort is taken with an SSRI.
Rationale 3: Renal failure is a sign of serotonin syndrome, which can occur when St. John's wort is taken with an SSRI.
Rationale 4:Tachycardia is incorrect because this combination does not affect heart rate.
Rationale 5:Hypotension is incorrect because this combination does not affect blood pressure.
Global Rationale: Mania is a sign of serotonin syndrome, which can occur when St. John's wort is taken with an SSRI. Confusion is a sign of serotonin syndrome, which can occur when St. John's wort is taken with an SSRI. Renal failure is a sign of serotonin syndrome, which can occur when St. John's wort is taken with an SSRI. Tachycardia is incorrect because this combination does not affect heart rate. Hypotension is incorrect because this combination does not affect blood pressure.
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