Tadalafil (Cialis) was prescribed 4 weeks ago for a patient with erectile dysfunction. The patient also takes prazosin (Minipress) for hypertension. Which statement by the patient best demonstrates understanding of the use of tadalafil (Cialis)?
a. "I can take this up to 2 times a day, just before intercourse."
b. "I have a little renal trouble, so I should take a higher dose."
c. "I should take this medication with food."
d. "I should take this medication no more than once a day."
ANS: D
Tadalafil should be taken no more than once a day and without regard to meals. Tadalafil has a half-life of 17.5 hours and should not be taken twice a day. Men with moderate renal or hepatic insufficiency should take a reduced dosage. This patient may be confusing the actions of tadalafil and prazosin.
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