The nurse preparing discharge medication instructions for a client with a history of hepatic disease who has been diagnosed with gouty arthritis and prescribed colchicine includes the following information in the discharge teaching: Select all
that apply. 1. Signs of medication toxicity include diarrhea, anorexia, and weakness.
2. Adverse reactions to the medication include sore throat, bruising, and fever.
3. Take medication as prescribed, but arrange schedule to coincide with meals.
4. Keep scheduled appointments for the monitoring of prothrombin time.
5. Maintain current weight with the inclusion of calorie-dense foods.
1. Signs of medication toxicity include diarrhea, anorexia, and weakness.
2. Adverse reactions to the medication include sore throat, bruising, and fever.
3. Take medication as prescribed, but arrange schedule to coincide with meals.
Rationale: Signs of medication toxicity include diarrhea, anorexia, and weakness. Observe for early signs of toxicity (colchicine): weakness, anorexia, nausea, vomiting, and diarrhea, especially in presence of cardiac, renal, or hepatic disease. Adverse reactions to the medication include sore throat, bruising, and fever. Observe for severe adverse effects: nausea, sore throat or mouth, fever, fatigue, unusual bleeding, or bruising (bone marrow depression). Take medication as prescribed but arrange schedule to coincide with meals. Give medications after a meal to reduce gastric distress. Keep scheduled appointments for the monitoring of prothrombin time. Prothrombin time is not usually monitored for clients prescribed colchicines. Maintain current weight with the inclusion of calorie-dense foods. Gouty arthritis is seen more frequently in clients who are overweight, so the inclusion of calorie-dense foods would not be encouraged.
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