A staphylococcal isolate that gives a negative result using the Cefinase disk and tests resistant to penicillin by disk diffusion means that:
a. the isolate may contain the mecA gene.
b. the bacteria produce the lactamase en-zyme.
c. the isolate is also resistant to ampicillin, carbenicillin, ticarcillin, and imipenem.
d. the isolate is also resistant to oxacillin, cefoxitin, and ticarcillin-clavulanate.
A
The negative Cefinase test indicates that the bacterium does not produce the lactamase en-zyme; the organism be expressing its resistance to Penicillin due to the presence of the mecA gene product, an altered Penicillin-Binding Protein (i.e., PBP2a).
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