For any patient receiving clozapine (Clozaril), which laboratory result should be reported to the physician?
1. Red blood cell (RBC) of 3.8 million cells/mL
2. Red blood cell (RBC) of 5.0 million cells/mL
3. White blood cell (WBC) of 3,800 cells/mcl
4. White blood cell (WBC) of 12,000 cells/mcl
Correct Answer: 3
Rationale: The normal white blood cell (WBC) count is 4,500–10,500 cells/mcl. A lower count indicates agranulocytosis, which is a life-threatening side effect of clozapine (Clozaril). A red blood cell (RBC) of 5.0 million cells/mL is a normal red blood cell (RBC) count. A white blood cell (WBC) of 12,000 cells/mcl is an elevated white blood cell (WBC) count and could indicate an infection, but it is not a side effect of clozapine (Clozaril). A red blood cell (RBC) of 3.8 million cells/mL is a low range of red blood cells (RBCs) and could indicate anemia, but it is not a side effect of clozapine (Clozaril).
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