A 75-year-old woman is taking medroxyprogesterone (Provera) for treatment of inoperable metastatic uterine carcinoma. The nurse would immediately collaborate with the prescriber if the patient's family made which statement?
1. "Mom seems much more depressed today."
2. "Mom's heart rate is faster today."
3. "Mom has a runny nose."
4. "Mom is more confused today."
5. "Mom has diarrhea today."
1,4
Rationale 1: Medroxyprogesterone should be used with caution in those with depression.
Rationale 2: Tachycardia is not an effect of medroxyprogesterone.
Rationale 3: Runny nose is not an effect of medroxyprogesterone.
Rationale 4: Women age 65 or older have increased risk for dementia when treated with progestins.
Rationale 5: Diarrhea is not an effect of medroxyprogesterone.
Global Rationale: Medroxyprogesterone should be used with caution in those with depression. Women age 65 or older have increased risk for dementia when treated with progestins. Tachycardia, runny nose, and diarrhea are not effects of medroxyprogesterone.
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