Why were native Americans so susceptible to European diseases such as smallpox and plague?

a. They had naturally weaker immune systems than Europeans.
b. They had been isolated from Africa, Asia, and Europe.
c. They lacked an understanding of germ theory and how to quarantine ill people.
d. They believed the Europeans were gods, so they had no fear of them or their diseases.


b. They had been isolated from Africa, Asia, and Europe.

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