A client is receiving a cell-cycle-specific medication for the treatment of leukemia. The nurse recognizes that in order for these drugs to kill the most cancer cells, they should be administered in:
1. divided, infrequent doses.
2. divided, frequent doses.
3. a single dose each day.
4. a large, one-time dose.
Correct Answer: 2
Rationale 1: This is not the most effective administration of cell-cycle-specific drugs.
Rationale 2: Cell-cycle-specific drugs kill the most cancer cells when administered in divided, frequent doses.
Rationale 3: This is not the most effective administration of cell-cycle-specific drugs.
Rationale 4: This is not the most effective administration of cell-cycle-specific drugs.
Global Rationale: Cell cycle specific drugs kill the most cancer cells when they are administered in divided but frequent doses. The other dosing schedules are not the most effective.
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