Ordered: Cerubidine® 22 mg/m2 IV q week On hand: Cerubidine® for injection. When reconstituted, each milliliter contains 5 mg of drug. The maximum recommended pediatric dosage is 25 mg/m2 IV the first day every week. Patient is 65 cm tall and weighs 20 kg. If this is a safe dose for this patient, determine amount to administer: ________. If it is not a safe dose, write: not safe.
Fill in the blank(s) with the appropriate word(s).
2.6 mL
Find the patient's BSA:
BSA = 0.577 m2, rounded to 0.58 m2
Calculate maximum dose:
H = 5 mg; Q = 1 mL; D = 25 mg/m2
D = 25 mg/m2 × 0.58 m2
D = 14.5 mg = maximum recommended dose
Calculate desired dose:
D = 22 mg/m2 × 0.58
D = 12.76 mg, rounded to 12.8 mg
The desired dose is less than the maximum recommended dose, so it is safe.
Calculate amount to administer:
A = 2.56 mL, rounded to 2.6 mL
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