When a drug enters the blood, it may bind to molecules such as albumin, which makes the drug inactive. This is termed
a. protein binding.
b. protein affinity.
c. drug action.
d. drug binding.
a. Drugs binding to plasma proteins is a reversible action. A highly protein-bound drug has a longer duration of action. Only a free drug, not bound to plasma proteins, is active. One drug may displace another form its binding site on the protein, elevating the free concentration of the displaced drug. This is a type of drug interaction. An example of a highly protein-bound drug is warfarin (a blood thinner).
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