A 40-year-old male who has been HIV positive for 6 years is experiencing a new increase in his viral load along with a corresponding decrease in his CD4+ count. Which of the following aspects of his immune system is likely to remain most intact?
A)
Presentation of major histocompatibility molecules on body cells
B)
Orchestration of natural killer cells as part of cell-mediated immunity
C)
Activation of B lymphocytes
D)
Phagocytic function of monocytes and macrophages
Ans:
A
Feedback:
The expression of MHC on various cells of the body is not noted to be directly influenced by HIV. However, infected CD4+ cells are compromised in their ability to guide the action of NK cells, to direct phagocytic function of macrophages, and to present antigens that activate B cells.
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