The health care provider prescribes hydrochlorothiazide (HCTZ) for a client in chronic renal failure. The nurse suspects the client is experiencing an ineffective response to the medication
Which clinical manifestation would be the most significant?
1. Hyponatremia
2. Excessive skin moisture
3. Rales
4. Hypertension
Correct Answer: 3
Rationale 1: Hyponatremia is an adverse effect associated with this medication, but it is not the most significant adverse effect noted.
Rationale 2: Excessive skin moisture is not an adverse effect associated with this medication.
Rationale 3: Rales can represent pulmonary edema, which is a life-threatening complication of chronic renal failure and fluid retention.
Rationale 4: Hypertension is not an adverse effect associated with this medication. Hypertension is the reason the medication is given.
Global Rationale: Rales can represent pulmonary edema, which is a life-threatening complication of chronic renal failure and fluid retention. Hyponatremia is an adverse effect associated with this medication, but it is not the most significant adverse effect noted. Excessive skin moisture is not an adverse effect associated with this medication. Hypertension is not an adverse effect associated with this medication. Hypertension is the reason the medication is given.
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