Place the class I processing pathway in the correct order
a. Peptides exported from the ER by TAP > peptides are digested by the proteasome > peptides are loaded onto class I > class I is exported to the cell surface
b. Proteins are digested by the proteasome > peptides are imported into the ER by TAP > peptides are loaded onto MHC class I > class I is exported to the cell surface
c. MHC class I moves from the cell surface to the lysosome by endocytosis > class I bound peptides are replaced with antigenic peptides in the lysosome > class I returns to the cell surface
d. Proteins are degraded by TAP > peptides are imported into the lysosome by the proteasome > peptide-MHC class I complexes are exported to the cell surface
e. MHC class I is transported to the ER by TAP > proteins in the ER are degraded into peptides by the proteasome > peptides bind MHC class I in the ER and the complex is exported to the cell surface
What will be an ideal response
B
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