What type of phagocytic cell lies between the layers of the renal capillaries?
a. Podocytes
b. Macula densa cells
c. Mesangial cells
d. Filtration slits
ANS: C
Mesangial cells lie between and support the capillaries. Mesangial cells have phagocytic ability similar to monocytes, release inflammatory cytokines, and can contract to regulate glomerular ca-pillary blood flow. The epithelium has specialized cells called podocytes from which pedicles (foot projections) radiate and adhere to the basement membrane. The macula densa are sodi-um-sensing cells. The pedicles interlock with the pedicles of adjacent podocytes, forming an elaborate network of intercellular clefts called filtration slits, or slit membranes.
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