When explaining to a class of nursing students the effects of dysregulation of the RANKL/RANK/OPG pathway, the instructor emphasizes that this plays a prominent role in the pathogenesis of: Select all that apply
A)
osteomalacia.
B)
neoplasia of the bone.
C)
osteoporosis.
D)
genu varum.
E)
bone necrosis.
Ans:
B, C
Feedback:
It is now believed that dysregulation of the RANKL/RANK/OPG pathway plays a prominent role in the pathogenesis of bone diseases such as neoplasia and bone lesions as well as osteoporosis. Avascular necrosis is known as bone necrosis (death) due to interruption to the blood supply of the bone.
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