Which definition describes a receptor?
1. A cell component to which a drug binds in a dose-dependent manner
2. Present only in the drug's target tissue
3. Required to drug action
4. Analogous to the "key" in the lock-and-key model of drug–receptor interaction
1
Rationale 1: A cell component to which a drug binds in a dose-dependent manner is a receptor.
Rationale 2:Receptors are present not only in the drug's target tissue, but also in many other tissues in the body. Drug effects at sites other than the target tissue often result in side effects.
Rationale 3:Although most drugs act via receptor-mediated mechanisms, some drugs do not act at specific receptors.
Rationale 4:A receptor is analogous to the "lock" in the lock-and-key model of drug–receptor interaction.
Global Rationale: A cell component to which a drug binds in a dose-dependent manner is a receptor. Receptors are present not only in the drug's target tissue, but also in many other tissues in the body. Drug effects at sites other than the target tissue often result in side effects. A receptor is analogous to the "lock" in the lock-and-key model of drug–receptor interaction.
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