Which theory of etiology of Alzheimer's disease, suggested by current research, might the nurse use to help a family understand that this disorder is not of psychosocial origin? Alzheimer's disease is associated with:
a. Abnormal serotonin reuptake
b. Prion infection of gray matter
c. ß-Amyloid protein deposits in the brain
d. Excessive acetylcholine in the frontal cortex
ANS: C
The prevailing theories of etiology of Alzheimer's disease include the following: angiopathy and blood-brain barrier incompetence; neurotransmitter and receptor deficiencies of acetyl-choline; abnormal proteins, specifically ß-amyloid and their products; and genetic defects. Neither serotonin nor prions are implicated as problems in Alzheimer's disease.
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