A 5-month-old child is admitted to the hospital with recurring respiratory infections. A possible cause of this condition is:
a. hypergammaglobulinemia.
b. increased maternal IgG.
c. immune insufficiency.
d. decreased maternal antibody breakdown, resulting in hyposensitivity.
ANS: C
Normal human infants are immunologically immature when born, with deficiencies in antibody production, phagocytic activity, and complement activity, especially components of alternative pathways. They do not possess hypergammaglobulinemia. Possessing increased maternal IgG would not lead to recurring infections. The recurrent infections are due to decreased immunity, not maternal antibody breakdown.
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