Colchicine is an alkaloid derived from plants. What is its effect on chromosome behavior?
A) By blocking DNA replication, chromosomes fail to migrate to the poles at anaphase; thus, homologous chromosomes end up in the same nucleus.
B) By blocking DNA replication, chromosomes do not undergo meiosis I and instead all gametes suffer from aneuploidy.
C) By interfering with spindle formation, replicated chromosomes fail to migrate to the poles at anaphase; thus, sister chromatids end up in the same nucleus.
D) By interfering with spindle formation, replicated chromosomes fail to migrate to the poles at anaphase; thus, homologous chromosomes end up in the same nucleus.
E) By blocking DNA replication, chromosomes do not undergo meiosis II and instead half the gametes are empty.
Answer: C
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