Which of the following infants would be more likely to have Rh incompatibility?
1. Infant of an Rh-negative mother and a father who is Rh positive and homozygous for the Rh factor
2. Infant who is Rh negative and mother is Rh negative
3. Infant of an Rh-negative mother and a father who is Rh positive and heterozyg-ous for the Rh factor
4. Infant who is Rh positive and mother who is Rh positive
1
1. Correct. If the mother is Rh negative and the father is Rh positive and homozygous for the Rh factor, all the offspring will be Rh positive. Only Rh-positive offspring of an Rh-negative mother are at risk for Rh incompatibility.
2. Incorrect. Only the Rh-positive offspring of an Rh-negative mother are at risk.
3. Incorrect. If the mother is Rh negative and the father is Rh positive and heterozygous for the factor, there is a 50% chance that each infant born of the union will be Rh positive and a 50% chance that each will be born Rh negative.
4. Incorrect. Only the Rh-positive offspring of an Rh-negative mother are at risk.
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