A nurse counsels a couple who have concerns about a sex-linked disorder. Both parents are carriers of the disorder. They ask the nurse how this disorder will affect any children they might have. What is the nurse's best response?
1. "If you have a daughter, she will not be affected."
2. "If you have a son, he will not be affected."
3. "There is a 25% chance that a daughter will have the disorder."
4. "There is a 50% chance that a son will be a carrier."
4
Rationale:
1. If both parents carry a sex-linked disorder, they each have one normal sex chromosome and one abnormal female sex chromosome.
2. There is a 50% chance of males being normal.
3. With female offspring, there is a 50% of being a carrier, and a 50% chance of having the disorder.
4. There is a 50% chance of male offspring being carriers.
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