Many non-LTR (target primed) retrotransposons encode a reverse transcriptase that has an endonuclease activity. What is the primary function of the endonuclease activity?
A. Its primary function is to cleave the 3' end of the transposon and initiate transposition.
B. Its primary function is to cleave the 5' end of the transposon and initiate transposition.
C. After the RNA intermediate is converted to a double-stranded DNA, the endonuclease cleaves the target site.
D. The endonuclease cleaves a phosphodiester bond in the target site, exposing the primer terminus that is required to prime reverse transcription of the RNA intermediate.
E. None of choices given describes the function of the endonuclease activity.
D
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