A patient has a systemic candidal infection, and the provider has ordered oral fluconazole (Diflucan) 400 mg on day 1 and 200 mg once daily thereafter. What will the nurse do?
a. Administer the drug as ordered.
b. Contact the provider to discuss cutting the dosing in half.
c. Contact the provider to discuss giving 400 mg on all days.
d. Contact the provider to discuss giving the drug intravenously.
ANS: A
The dosing for fluconazole for systemic candidal infections is 400 mg on the first day and 200 mg/day each day thereafter. Dosing for oral or esophageal candidal infections is half that for systemic infections. It is not correct to give 400 mg on all days of therapy. Fluconazole is as effective when given orally as it is when given intravenously.
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