Which drug administration route is most likely to result in reduced drug bioavailability?
a. Enteral
b. Intravenous
c. Transdermal
d. Subcutaneous
A
The enteral route involves using the GI system. Not all drugs are completely absorbed from this area, and because drugs absorbed in the GI tract first undergo some liver metabolism before en-tering systemic circulation (resulting in first pass loss), drugs administered enterally always have a lower bioavailability than those administered by the parenteral route.
You might also like to view...
Which is safe?
a. A three-pronged plug b. A frayed cord c. Cracked or chipped items d. An overloaded electrical outlet
The client receives cyclophosphamide (Cytoxan). The nurse evaluates the client's laboratory work. Which laboratory finding would support canceling the client's next treatment with this drug?
1. Hemoglobin of 14 g/dl 2. Blood urea nitrogen of 12 mg/dl 3. WBC count of 8,000 cells/mcl 4. Platelet count of 8,000/mm
A nurse working in a rehabilitation facility has a physician's prescription to contact other therapists as required by patient need. A patient has started to have difficulty with bathing and grooming
Which therapist should the nurse contact to assist the patient to regain these skills? a. Physical therapist b. Occupational therapist c. Speech-language pathologist d. Respiratory therapist
Clients with chewing difficulties should have
a. a full-liquid diet b. a low-residue diet c. a bland diet d. a soft diet