The nurse administers a human B-type natriuretic peptide with the expectation it will have what action?
A) Decrease blood volume
B) Increase force of cardiac contraction
C) Reduce venous return
D) Lighten the heart's workload
C
Feedback:
Human B-type natriuretic peptides are normally produced by myocardial cells as a compensatory response to increased cardiac workload and increased stimulation by the stress hormones. They bind to endothelial cells, leading to dilation and resulting in decreased venous return, peripheral resistance, and cardiac workload. They also suppress the body's response to the stress hormones, leading to increased fluid loss and further decrease in cardiac workload. Diuretics decrease blood volume, cardiac glycosides increase force of contraction, and vasodilators lighten the heart's workload.
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