Why is lipid diffusion an important mechanism for drug absorption?
a. Many epithelial membranes must be crossed if a drug is to distribute in the body and reach its target organ.
b. Epithelial cells do not have lipid membranes, so a drug must be water-soluble to diffuse across such a membrane.
c. It is directly related to the proportion of a drug that reaches the systemic circulation.
d. Lipid diffusion has no importance in drug absorption because the body has very few epithelial membranes drugs must cross.
ANS: A
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