What is the primary mechanism of action of tiagabine in the treatment of partial seizures?
A. Interference with both Na + and Ca++ ion channel activity to inhibit the high-frequency firing of neurons
B. Blockade of the neuronal reuptake of the inhibitory transmitter GABA back into its nerve endings
C. Inactivation of Na+ ion channels to decrease high-frequency firing of neurons
D. Blockade of Ca++ ion channels and decreased release of the excitatory neurotransmitter glutamate
Answer: B
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