A 28-year-old woman suspected of having sepsis caused by G. vaginalis has multiple blood cultures drawn; however, all sets were negative. Which one of the following statements explains this discrepancy?
a. The lot of blood culture media is most likely defective.
b. The blood culture bottles should be incu-bated anaerobically to enhance the growth of the organism.
c. G. vaginalis is inhibited by sodium po-lyanethol sulfonate (SPS) in the blood culture.
d. No discrepancy is present. G. vaginalis remains localized and does not cause sep-sis.
C
Gardnerella is inhibited by SPS, which currently is used as an anticoagulant in most commercial blood culture media. An SPS-free medium or a medium with SPS that is supplemented with ge-latin should be used when G. vaginalis sepsis is suspected.
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