A nurse administers medications to a client who has asthma. Which medication classification is paired correctly with its physiologic response to the medication?
a. Bronchodilator - Stabilizes the membranes of mast cells and prevents the release of inflammatory mediators
b. Cholinergic antagonist - Causes bronchodilation by inhibiting the parasympathetic nervous system
c. Corticosteroid - Relaxes bronchiolar smooth muscles by binding to and activating pulmonary beta2 receptors
d. Cromone - Disrupts the production of pathways of inflammatory mediators
ANS: B
Cholinergic antagonist drugs cause bronchodilation by inhibiting the parasympathetic nervous system. This allows the sympathetic nervous system to dominate and release norepinephrine that actives beta2 receptors. Bronchodilators relax bronchiolar smooth muscles by binding to and activating pulmonary beta2 receptors. Corticosteroids disrupt the production of pathways of inflammatory mediators. Cromones stabilize the membranes of mast cells and prevent the release of inflammatory mediators.
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