Because they must pass through the ________________, ionized drugs are poorly distributed
A. intestinal wall
B. blood–brain barrier
C. liver
D. heart
b
Rationale: Ionized drugs must pass through the blood–brain barrier to be absorbed, making their distribution more difficult. The intestinal wall, bloodstream, and heart are incorrect choices because all of these do not necessarily affect the distribu-tion of ionized drugs.
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