What bone marrow sample is best to determine fat-to-cell ratio and overall cellularity, as well as for searching for malignant cells?
a. Core biopsy
b. Aspirate smears
c. Peripheral blood
d. Prussian blue stain
ANS: A
The core biopsy is the best sample for determining overall cellularity, fat-to-cell ratio, and searching for malignant cells. It provides an intact portion of the bone marrow.
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