How do Sertoli cells protect the developing sperm? What do they do exactly?
What will be an ideal response?
Answer: Sperm cells are made through a process called as spermatogenesis. This begins at the seminiferous tubules , where the spermatozoa undergo mitotic division.These spermatozoa are released into the lumen i.e, the center of the tubule. The Sertoli cells are presesnt in the walls of the seminiferous tubules.They help in nursing these sperm cell sthrough this process of maturation. Sertoli cells develop a barrier between blood and testis, to prevent any toxins or bacteria entering ,while sperms are developing. If sperm cells enter into blood stream, they may be attacked by the body's own immune system. So the sertoli cells form structures called 'tight junctions', which divides seminiferous tubules into 2 parts. One part touches lymph and blood, the other part with which cells have no contact with these substances.Physically these sertoli cells donot contribute to spermatogenesis but, they create an environment for the survival of testicular germ cells or sperm cells.
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