Daily co-administration of both aspirin and ibuprofen can ________ the overall antiplatelet effects of aspirin because ________.

A. delay; aspirin interferes with ibuprofen's inactivation of COX-1 enzyme
B. increase; ibuprofen is a COX-1 enhancer and has the ability to alter the active site on COX and inhibit thromboxane production
C. cancel; ibuprofen is a COX-1 inhibitor and can occupy the same enzymatic site in the platelets but does not have the ability to alter the active site on COX or inhibit thromboxane production
D. have no effect on; ibuprofen seldom interferes with platelet aggregation


Answer: C

Nursing

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