With regard to substance abuse, tolerance is defined as a:
A. chronic disorder characterized by the compulsive use of a substance that results in physical or psychological harm.
B. physiologic adaptation to the effects of a drug such that increasingly larger doses are required to achieve the same effect.
C. physiologic state of adaptation to a drug, which is characterized by withdrawal symptoms if the drug is stopped.
D. predictable set of signs and symptoms that occurs after the abrupt cessation of a drug or after rapidly decreasing the dosage
Ans: B. physiologic adaptation to the effects of a drug such that increasingly larger doses are required to achieve the same effect.
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